Abstract :The novel coronavirus (nCOVID-19) with potential for human-to-human transmission at an exponential rate across the globe has been shown in numerous reports. According to WHO declaration COVID-19 is a global emergency with over 40 million infections that could cause 1-5 million deaths. Currently Pakistan is acutely facing this key challenge with lockdown and casualties. On February 25, 2020, the (COVID-19) first case was reported in Karachi (Sindh) from a pilgrim and rapidly spread throughout Pakistan. As of October 25, 2020, a total of 320,211 cases have been confirmed in the 4 Pakistani provinces, the capital Islamabad and the two autonomous.